13c Urea Breath In The Diagnosis Of H.pylori Infection

Helicobacter pylori infection refers to the local infection of Helicobacter pylori bacteria. Helicobacter pylori is a special type of bacteria that is resistant to strong acids and can multiply in strong acids. It can survive for a long time in the gastric juice and easily lead to repeated gastric mucosal infections. Clinically, a small amount of Helicobacter pylori can also be found in oral secretions and excrements. The main route of infection is intimate contact, such as kissing, sharing meals, sharing toiletries, etc., which can cause morning retching, bloating, abdominal pain, acid reflux, heartburn, etc. Symptoms are the primary cause of gastric ulcer and gastric cancer.

13C ubt test is a non-radioactive isotope that can be used safely for repeated testing, which is frequently required in clinical practice, and for detecting H pylori infection in children and women of childbearing age. 

Furthermore, 13C-urea has been the most widely used substrate in methodological studies performed to validate this kind of diagnostic test. Another relevant advantage of using the stable isotope is that breath samples can be sent by post or courier to remote analysis centres, thus promoting the distribution of the test, which can even be performed at home if the patients are adequately selected and instructed.